Organophosphate Flame Retardants Act as Endocrine-Disrupting Chemicals in MA-10 Mouse Tumor Leydig Cells.

Schang, Gauthier; Robaire, Bernard; Hales, Barbara F

Schang, Gauthier; Robaire, Bernard; Hales, Barbara F.

Affiliation

Schang G; *Department of Pharmacology and Therapeutics and.
Robaire B; *Department of Pharmacology and Therapeutics and Department of Obstetrics and Gynecology, McGill University, Montreal, Quebec H3G 1Y6, Canada bernard.robaire@mcgill.ca.
Hales BF; *Department of Pharmacology and Therapeutics and.

Toxicol Sci ; 150(2): 499-509, 2016 Apr.

Article in En | MEDLINE | ID: mdl-26794138

Subject(s)

Endocrine Disruptors/toxicity; Flame Retardants/toxicity; Leydig Cells/drug effects; Organophosphates/toxicity; Animals; Cell Culture Techniques; Cell Line, Tumor; Cell Survival/drug effects; Endocrine Disruptors/chemistry; Leydig Cells/metabolism; Leydig Cells/pathology; Male; Mice; Mitochondria/drug effects; Mitochondria/metabolism; Organophosphates/chemistry; Oxidative Stress/drug effects; Progesterone/biosynthesis; Superoxide Dismutase/metabolism

Key words

BFRs.; flame retardants; oxidative stress; replacement chemicals; steroidogenesis

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Full text: 1 Database: MEDLINE Main subject: Organophosphates / Endocrine Disruptors / Flame Retardants / Leydig Cells Limits: Animals Language: En Year: 2016 Type: Article

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