Cellular localisation of the kinin B1R in the pancreas of streptozotocin-treated rat and the anti-diabetic effect of the antagonist SSR240612.

Tidjane, Nejla; Gaboury, Louis; Couture, Réjean

Tidjane, Nejla; Gaboury, Louis; Couture, Réjean.

Biol Chem ; 397(4): 323-36, 2016 Apr.

Article in En | MEDLINE | ID: mdl-26841446

Subject(s)

Diabetes Mellitus, Experimental/drug therapy; Diabetes Mellitus, Experimental/metabolism; Dioxoles/pharmacology; Hypoglycemic Agents/pharmacology; Pancreas/drug effects; Pancreas/pathology; Receptor, Bradykinin B1/metabolism; Sulfonamides/pharmacology; Animals; Diabetes Mellitus, Experimental/pathology; Dioxoles/chemistry; Dioxoles/therapeutic use; Dose-Response Relationship, Drug; Hypoglycemic Agents/chemistry; Hypoglycemic Agents/therapeutic use; Male; Pancreas/metabolism; Rats; Rats, Sprague-Dawley; Streptozocin; Structure-Activity Relationship; Sulfonamides/chemistry; Sulfonamides/therapeutic use

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Full text: 1 Database: MEDLINE Main subject: Pancreas / Sulfonamides / Receptor, Bradykinin B1 / Diabetes Mellitus, Experimental / Dioxoles / Hypoglycemic Agents Limits: Animals Language: En Year: 2016 Type: Article

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