Coinhibitory Pathways in Immunotherapy for Cancer.

Baumeister, Susanne H; Freeman, Gordon J; Dranoff, Glenn; Sharpe, Arlene H

Baumeister, Susanne H; Freeman, Gordon J; Dranoff, Glenn; Sharpe, Arlene H.

Affiliation

Baumeister SH; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215.
Freeman GJ; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215.
Dranoff G; Division of Pediatric Hematology-Oncology, Boston Children's Hospital, Boston, Massachusetts 02115.
Sharpe AH; Harvard Medical School, Boston, Massachusetts 02115.

Annu Rev Immunol ; 34: 539-73, 2016 05 20.

Article in En | MEDLINE | ID: mdl-26927206

Subject(s)

Antibodies, Monoclonal/therapeutic use; B7-H1 Antigen/immunology; CTLA-4 Antigen/immunology; Immunotherapy/methods; Neoplasms/therapy; Programmed Cell Death 1 Receptor/immunology; T-Lymphocytes/immunology; Animals; Humans; Immunotherapy/trends; Lymphocyte Activation/drug effects; Neoplasms/immunology; Tumor Escape; Tumor Microenvironment

Key words

CTLA-4; PD-1; PD-L1; cancer immunotherapy; tumor immunity

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Full text: 1 Database: MEDLINE Main subject: T-Lymphocytes / B7-H1 Antigen / CTLA-4 Antigen / Programmed Cell Death 1 Receptor / Immunotherapy / Antibodies, Monoclonal / Neoplasms Limits: Animals / Humans Language: En Year: 2016 Type: Article

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