Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome.

Van De Pette, Matthew; Tunster, Simon J; McNamara, Grainne I; Shelkovnikova, Tatyana; Millership, Steven; Benson, Lindsay; Peirson, Stuart; Christian, Mark; Vidal-Puig, Antonio; John, Rosalind M

Van De Pette, Matthew; Tunster, Simon J; McNamara, Grainne I; Shelkovnikova, Tatyana; Millership, Steven; Benson, Lindsay; Peirson, Stuart; Christian, Mark; Vidal-Puig, Antonio; John, Rosalind M.

Affiliation

Van De Pette M; School of Biosciences, Cardiff University, Cardiff, United Kingdom.
Tunster SJ; School of Biosciences, Cardiff University, Cardiff, United Kingdom.
McNamara GI; School of Biosciences, Cardiff University, Cardiff, United Kingdom.
Shelkovnikova T; School of Biosciences, Cardiff University, Cardiff, United Kingdom.
Millership S; MRC Clinical Sciences Centre, Hammersmith Hospital, London, United Kingdom.
Benson L; Nuffield Department of Clinical Neuroscience, Nuffield Laboratory of Ophthalmology, John Radcliffe Hospital, Oxford, United Kingdom.
Peirson S; Nuffield Department of Clinical Neuroscience, Nuffield Laboratory of Ophthalmology, John Radcliffe Hospital, Oxford, United Kingdom.
Christian M; Division of Translational and Systems Medicine, Warwick Medical School, University of Warwick, Coventry, United Kingdom.
Vidal-Puig A; Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom.
John RM; School of Biosciences, Cardiff University, Cardiff, United Kingdom.

PLoS Genet ; 12(3): e1005916, 2016 Mar.

Article in En | MEDLINE | ID: mdl-26963625

Subject(s)

Adipose Tissue, Brown/growth & development; Cyclin-Dependent Kinase Inhibitor p57/metabolism; DNA-Binding Proteins/metabolism; Genomic Imprinting; Silver-Russell Syndrome/genetics; Transcription Factors/metabolism; Adipose Tissue, Brown/metabolism; Adipose Tissue, White/metabolism; Adult; Animals; Body Temperature; Cyclin-Dependent Kinase Inhibitor p57/genetics; DNA-Binding Proteins/genetics; Disease Models, Animal; Humans; Mice; Mitochondria/metabolism; Mitochondria/pathology; Mutation; Phenotype; Silver-Russell Syndrome/metabolism; Silver-Russell Syndrome/pathology; Transcription Factors/genetics

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Full text: 1 Database: MEDLINE Main subject: Transcription Factors / Adipose Tissue, Brown / Genomic Imprinting / DNA-Binding Proteins / Cyclin-Dependent Kinase Inhibitor p57 / Silver-Russell Syndrome Type of study: Prognostic_studies Limits: Adult / Animals / Humans Language: En Year: 2016 Type: Article

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