Structure and Function of the Mitochondrial Ribosome.
Annu Rev Biochem
; 85: 103-32, 2016 Jun 02.
Article
in En
| MEDLINE
| ID: mdl-27023846
ABSTRACT
Mitochondrial ribosomes (mitoribosomes) perform protein synthesis inside mitochondria, the organelles responsible for energy conversion and adenosine triphosphate production in eukaryotic cells. Throughout evolution, mitoribosomes have become functionally specialized for synthesizing mitochondrial membrane proteins, and this has been accompanied by large changes to their structure and composition. We review recent high-resolution structural data that have provided unprecedented insight into the structure and function of mitoribosomes in mammals and fungi.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Protein Biosynthesis
/
DNA, Mitochondrial
/
Mitochondrial Proteins
/
Ribosome Subunits
/
Mitochondrial Ribosomes
/
Mitochondria
Limits:
Animals
Language:
En
Year:
2016
Type:
Article