Equol suppresses inflammatory response and bone erosion due to rheumatoid arthritis in mice.

Lin, I-Chian; Yamashita, Shuya; Murata, Motoki; Kumazoe, Motofumi; Tachibana, Hirofumi

Lin, I-Chian; Yamashita, Shuya; Murata, Motoki; Kumazoe, Motofumi; Tachibana, Hirofumi.

Affiliation

Lin IC; Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka, 812-8581, Japan.
Yamashita S; Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka, 812-8581, Japan.
Murata M; Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka, 812-8581, Japan.
Kumazoe M; Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka, 812-8581, Japan.
Tachibana H; Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka, 812-8581, Japan. Electronic address: tatibana@agr.kyushu-u.ac.jp.

J Nutr Biochem ; 32: 101-6, 2016 06.

Article in En | MEDLINE | ID: mdl-27142742

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal/therapeutic use; Arthritis, Rheumatoid/diet therapy; Bone Resorption/prevention & control; Dietary Supplements; Equol/therapeutic use; Osteochondritis/prevention & control; Phytoestrogens/therapeutic use; Adaptor Proteins, Signal Transducing; Animals; Arthritis, Rheumatoid/diagnostic imaging; Arthritis, Rheumatoid/immunology; Arthritis, Rheumatoid/physiopathology; Autoimmunity; Bone Density; Bone Resorption/etiology; Bone and Bones/diagnostic imaging; Bone and Bones/immunology; Bone and Bones/metabolism; Down-Regulation; Extracellular Matrix Proteins/genetics; Extracellular Matrix Proteins/metabolism; Forelimb; Glycoproteins/genetics; Glycoproteins/metabolism; Intercellular Signaling Peptides and Proteins; Interleukin-6/antagonists & inhibitors; Interleukin-6/genetics; Interleukin-6/metabolism; Male; Mice, Inbred DBA; Osteochondritis/etiology; Phosphoproteins/genetics; Phosphoproteins/metabolism; Receptors, Interleukin-6/antagonists & inhibitors; Receptors, Interleukin-6/genetics; Receptors, Interleukin-6/metabolism; Specific Pathogen-Free Organisms; Synovitis/etiology; Synovitis/prevention & control; X-Ray Microtomography

Key words

Bone erosion; Cartilage degradation; Equol; Inflammation; Rheumatoid arthritis

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Full text: 1 Database: MEDLINE Main subject: Osteochondritis / Arthritis, Rheumatoid / Bone Resorption / Anti-Inflammatory Agents, Non-Steroidal / Dietary Supplements / Phytoestrogens / Equol Type of study: Etiology_studies Language: En Year: 2016 Type: Article

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