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Optimization of isoxazoline amide benzoxaboroles for identification of a development candidate as an oral long acting animal ectoparasiticide.
Zhang, Yong-Kang; Plattner, Jacob J; Easom, Eric E; Akama, Tsutomu; Zhou, Yasheen; White, W Hunter; Defauw, Jean M; Winkle, Joseph R; Balko, Terry W; Cao, Jianxin; Ge, Zhixin; Yang, Jianzhang.
Affiliation
  • Zhang YK; Anacor Pharmaceuticals, Inc., 1020 E. Meadow Circle, Palo Alto, CA 94303, USA.
  • Plattner JJ; Anacor Pharmaceuticals, Inc., 1020 E. Meadow Circle, Palo Alto, CA 94303, USA.
  • Easom EE; Anacor Pharmaceuticals, Inc., 1020 E. Meadow Circle, Palo Alto, CA 94303, USA.
  • Akama T; Anacor Pharmaceuticals, Inc., 1020 E. Meadow Circle, Palo Alto, CA 94303, USA.
  • Zhou Y; Anacor Pharmaceuticals, Inc., 1020 E. Meadow Circle, Palo Alto, CA 94303, USA.
  • White WH; Elanco Animal Health Research and Development, A Division of Eli Lilly & Company, 2500 Innovation Way, Greenfield, IN 46140, USA.
  • Defauw JM; Elanco Animal Health Research and Development, A Division of Eli Lilly & Company, 2500 Innovation Way, Greenfield, IN 46140, USA.
  • Winkle JR; Elanco Animal Health Research and Development, A Division of Eli Lilly & Company, 2500 Innovation Way, Greenfield, IN 46140, USA.
  • Balko TW; Elanco Animal Health Research and Development, A Division of Eli Lilly & Company, 2500 Innovation Way, Greenfield, IN 46140, USA.
  • Cao J; Shanghai ChemPartner, 998 Halei Road, Zhangjiang High-tech Park, Pudong New Area, Shanghai 201203, China.
  • Ge Z; Shanghai ChemPartner, 998 Halei Road, Zhangjiang High-tech Park, Pudong New Area, Shanghai 201203, China.
  • Yang J; Sundia MediTech Company, Ltd, Building 8, 388 Jialilue Road, Zhangjiang High-Tech Park, Shanghai 201203, China.
Bioorg Med Chem Lett ; 26(13): 3182-3186, 2016 07 01.
Article in En | MEDLINE | ID: mdl-27210432
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Full text: 1 Database: MEDLINE Main subject: Boron Compounds / Dermacentor / Ectoparasitic Infestations / Ctenocephalides / Amides / Isoxazoles / Antiparasitic Agents Type of study: Diagnostic_studies Limits: Animals Language: En Year: 2016 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Boron Compounds / Dermacentor / Ectoparasitic Infestations / Ctenocephalides / Amides / Isoxazoles / Antiparasitic Agents Type of study: Diagnostic_studies Limits: Animals Language: En Year: 2016 Type: Article