Direct Construction of 2-Aryliminochromenes from Arynes, N,S-Keteneacetals, and DMF.
J Org Chem
; 81(14): 5942-8, 2016 07 15.
Article
in En
| MEDLINE
| ID: mdl-27266363
ABSTRACT
A concise and direct synthetic strategy for the construction of 2-aryliminochromene skeleton by cascade three-component coupling reaction of arynes, N,S-keteneacetals, and DMF in good yields has been disclosed. The process demonstrates the first example of aryne chemistry combined with N,S-keteneacetals. Using this strategy, an expeditious synthesis of biologically important arylimino-2H-chromene-3- carboxamides was achieved.
Full text:
1
Database:
MEDLINE
Language:
En
Year:
2016
Type:
Article