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Bioluminescent Probe for Detecting Mercury(II) in Living Mice.
Jiang, Tianyu; Ke, Bowen; Chen, Hui; Wang, Weishan; Du, Lupei; Yang, Keqian; Li, Minyong.
Affiliation
  • Jiang T; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (MOE), School of Pharmaceutical Sciences, Shandong University , Jinan, Shandong 250012, China.
  • Ke B; Laboratory of Anaesthesiology and Critical Care Medicine, Translational Neuroscience Center, West China Hospital, Sichuan University , Chengdu, Sichuan 610041, China.
  • Chen H; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (MOE), School of Pharmaceutical Sciences, Shandong University , Jinan, Shandong 250012, China.
  • Wang W; Laboratory of Anaesthesiology and Critical Care Medicine, Translational Neuroscience Center, West China Hospital, Sichuan University , Chengdu, Sichuan 610041, China.
  • Du L; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences , Beijing 100190, China.
  • Yang K; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (MOE), School of Pharmaceutical Sciences, Shandong University , Jinan, Shandong 250012, China.
  • Li M; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences , Beijing 100190, China.
Anal Chem ; 88(15): 7462-5, 2016 08 02.
Article in En | MEDLINE | ID: mdl-27412583
ABSTRACT
A novel bioluminescence probe for mercury(II) was obtained on the basis of the distinct deprotection reaction of dithioacetal to decanal, so as to display suitable sensitivity and selectivity toward mercury(II) over other ions with bacterial bioluminescence signal. These experimental results indicated such a probe was a novel promising method for mercury(II) bioluminescence imaging in environmental and life sciences ex vivo and in vivo.
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Full text: 1 Database: MEDLINE Main subject: Luminescent Agents / Mercury Limits: Animals Language: En Year: 2016 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Luminescent Agents / Mercury Limits: Animals Language: En Year: 2016 Type: Article