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Emergence and Plasmid Analysis of Klebsiella pneumoniae KP01 Carrying blaGES-5 from Guangzhou, China.
Chen, Ding-Qiang; Wu, Ai-Wu; Yang, Ling; Su, Dan-Hong; Lin, Yong-Ping; Hu, Yan-Wei; Zheng, Lei; Wang, Qian.
Affiliation
  • Chen DQ; Laboratory Medicine Centre, Nanfang Hospital, Southern Medical University, Guangzhou, China Department of Laboratory Medicine, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Wu AW; Department of Clinical Microbiology, KingMed College of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.
  • Yang L; Department of Laboratory Medicine, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Su DH; Department of Laboratory Medicine, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Lin YP; Department of Laboratory Medicine, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Hu YW; Laboratory Medicine Centre, Nanfang Hospital, Southern Medical University, Guangzhou, China.
  • Zheng L; Laboratory Medicine Centre, Nanfang Hospital, Southern Medical University, Guangzhou, China.
  • Wang Q; Laboratory Medicine Centre, Nanfang Hospital, Southern Medical University, Guangzhou, China nfyywangqian@163.com.
Antimicrob Agents Chemother ; 60(10): 6362-4, 2016 10.
Article in En | MEDLINE | ID: mdl-27431225
ABSTRACT
Klebsiella pneumoniae strain KP01 carrying blaGES-5 was identified from a patient in Guangzhou, China. High-throughput sequencing assigned blaGES-5 to a 28.5-kb nonconjugative plasmid, pGES-GZ. A 13-kb plasmid backbone sequence on pGES-GZ was found to share high sequence identities with plasmids from Gram-negative nonfermenters. A novel class 1 integron carrying a gene cassette array of orf28-orf28-blaGES-5 was identified on pGES-GZ, within which orf28 encoded a hypothetical protein possibly correlated to fosfomycin resistance.
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Full text: 1 Database: MEDLINE Main subject: Bacterial Proteins / Beta-Lactamases / Klebsiella pneumoniae Limits: Aged / Humans / Male Country/Region as subject: Asia Language: En Year: 2016 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Bacterial Proteins / Beta-Lactamases / Klebsiella pneumoniae Limits: Aged / Humans / Male Country/Region as subject: Asia Language: En Year: 2016 Type: Article