In Silico and In Vitro Evaluation of Cytotoxic Activities of Farnesiferol C and Microlobin on MCF-7, HeLa and KYSE Cell Lines.

Aldaghi, L; Rad, A; Arab, A; Kasaian, J; Iranshahi, M; Sadr, A S; Soltani, F

Aldaghi, L; Rad, A; Arab, A; Kasaian, J; Iranshahi, M; Sadr, A S; Soltani, F.

Affiliation

Aldaghi L; Cellular and Molecular Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran.
Rad A; Cellular and Molecular Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran.
Arab A; Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Kasaian J; Natural Products and Medicinal Plants Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran.
Iranshahi M; Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Sadr AS; Bioinformatics Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran.
Soltani F; Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Drug Res (Stuttg) ; 66(10): 532-538, 2016 Oct.

Article in En | MEDLINE | ID: mdl-27463028

Subject(s)

Coumarins/pharmacology; Molecular Docking Simulation; Sesquiterpenes/pharmacology; Antineoplastic Agents/pharmacology; Apoptosis/drug effects; Cell Line, Tumor; Cell Survival/drug effects; Coumarins/isolation & purification; Dose-Response Relationship, Drug; Ferula/chemistry; Humans; Protein Binding; Proto-Oncogene Proteins c-bcl-2/metabolism; Sesquiterpenes/isolation & purification; bcl-2 Homologous Antagonist-Killer Protein/metabolism; bcl-2-Associated X Protein/metabolism

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PubMed Links

Database: MEDLINE Main subject: Sesquiterpenes / Coumarins / Molecular Docking Simulation Limits: Humans Language: En Year: 2016 Type: Article

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PubMed Links

Database: MEDLINE Main subject: Sesquiterpenes / Coumarins / Molecular Docking Simulation Limits: Humans Language: En Year: 2016 Type: Article