Different expression of sodium-iodide importer (NIS) between lactating breast and thyroid tissues may be due to structural difference of thyroid-stimulating hormone receptor (TSHR).

Shi, X-Z; Xue, L; Jin, X; Xu, P; Jia, S; Shen, H-M

Shi, X-Z; Xue, L; Jin, X; Xu, P; Jia, S; Shen, H-M.

Affiliation

Shi XZ; Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University; Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province and Ministry of Health (23618504), Harbin, 150081, China.
Xue L; Department of Epidemiology, Public Health School, Shenyang Medical College, Shenyang, China.
Jin X; Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University; Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province and Ministry of Health (23618504), Harbin, 150081, China.
Xu P; Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University; Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province and Ministry of Health (23618504), Harbin, 150081, China.
Jia S; Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University; Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province and Ministry of Health (23618504), Harbin, 150081, China.
Shen HM; R.D. Center, PacificBio Inc., Irvine, CA, 92602, USA.

J Endocrinol Invest ; 40(1): 41-48, 2017 Jan.

Article in En | MEDLINE | ID: mdl-27531173

Subject(s)

Biomarkers/metabolism; Breast/metabolism; Gene Expression Regulation; Lactation/physiology; Receptors, Thyrotropin/chemistry; Symporters/metabolism; Thyroid Gland/metabolism; Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Cells, Cultured; Female; Fluorescent Antibody Technique; Immunoenzyme Techniques; Male; Mice; Mice, Inbred BALB C; Real-Time Polymerase Chain Reaction; Receptors, Thyrotropin/genetics; Receptors, Thyrotropin/metabolism; Signal Transduction; Symporters/genetics

Key words

Lactating breast; NIS expression; TSHR cDNA sequences; Thyroid tissues

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Full text: 1 Database: MEDLINE Main subject: Thyroid Gland / Receptors, Thyrotropin / Breast / Lactation / Biomarkers / Gene Expression Regulation / Symporters Limits: Animals Language: En Year: 2017 Type: Article

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