Cell Adhesion Molecules, Neuronal/metabolism; Receptors, Notch/metabolism; Animals; Benzazepines/pharmacology; Cadherins/genetics; Cadherins/metabolism; Cell Adhesion Molecules, Neuronal/antagonists & inhibitors; Cell Adhesion Molecules, Neuronal/genetics; Cell Line, Tumor; Cell Movement/drug effects; Diamines/pharmacology; Down-Regulation/drug effects; Enzyme Inhibitors/pharmacology; HEK293 Cells; Human Umbilical Vein Endothelial Cells; Humans; Intracellular Signaling Peptides and Proteins; Jagged-1 Protein/pharmacology; Lung Neoplasms/metabolism; Lung Neoplasms/pathology; Membrane Glycoproteins; Mice; Mice, Inbred NOD; Mice, SCID; Microscopy, Fluorescence; Promoter Regions, Genetic; RNA Interference; RNA, Messenger/metabolism; RNA, Small Interfering/metabolism; Receptors, Notch/antagonists & inhibitors; Receptors, Notch/genetics; Signal Transduction/drug effects; Snail Family Transcription Factors/genetics; Snail Family Transcription Factors/metabolism; Thiazoles/pharmacology; Transplantation, Heterologous; Up-Regulation/drug effects