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MR-guided percutaneous sclerotherapy of low-flow vascular malformations: Clinical experience using a 1.5 tesla MR system.
O'Mara, Daniel M; DiCamillo, Paul A; Gilson, Wesley D; Herzka, Daniel A; Wacker, Frank K; Lewin, Jonathan S; Weiss, Clifford R.
Affiliation
  • O'Mara DM; Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • DiCamillo PA; Vascular and Interventional Radiology, Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Gilson WD; Siemens Healthcare USA, Baltimore, Maryland, USA.
  • Herzka DA; Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Wacker FK; Institute for Diagnostic and Interventional Radiology, Medical School Hanover, Hanover, Germany.
  • Lewin JS; Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Weiss CR; Vascular and Interventional Radiology, Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
J Magn Reson Imaging ; 45(4): 1154-1162, 2017 04.
Article in En | MEDLINE | ID: mdl-27796061
ABSTRACT

PURPOSE:

To demonstrate the feasibility, safety, and effectiveness of image-guided sclerotherapy of low-flow vascular malformations using a 1.5 Tesla (T) MR scanner with real-time imaging capability and in-suite fluoroscopy. MATERIALS AND

METHODS:

Thirty-three procedures were performed with real-time 1.5T MR-guidance on 22 patients with a vascular malformation in the neck (n = 2), chest (n = 6), abdomen and pelvis (n = 15), and extremities (n = 11). Quantitative analysis was performed for changes in (a) planning time, (b) targeting time (interval between needle skin puncture and lesion access), (c) intervention time (interval between needle skin puncture and needle removal), and (d) total procedure time. Qualitative analysis was performed for (a) success of therapy and (b) occurrence of complications.

RESULTS:

Technical success was achieved in 29 of 33 procedures. The average planning time did not significantly change between the first seven procedures and the last seven procedures (P = 0.447). The average targeting time decreased by 02445 (hoursminutesseconds) (P = 0.043), the average intervention time decreased by 02658 (P = 0.022), and the average procedure time decreased by 02841 (P = 0.046) when comparing the first seven procedures and the last seven procedures. Overall, there was an improvement in the patients' predominant symptoms following 82% of procedures, including a significant decrease in average pain following therapy (P < 0.001). There was a minor complication rate of 3% with no major complications.

CONCLUSION:

MR-guided percutaneous sclerotherapy seems to be a safe, effective, and versatile technique for treating low-flow vascular malformations. LEVEL OF EVIDENCE 3 J. Magn. Reson. Imaging 2017;451154-1162.
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Full text: 1 Database: MEDLINE Main subject: Sclerotherapy / Magnetic Resonance Imaging, Interventional / Vascular Malformations Type of study: Guideline / Qualitative_research Limits: Adolescent / Adult / Child / Female / Humans / Male / Middle aged Language: En Year: 2017 Type: Article

Full text: 1 Database: MEDLINE Main subject: Sclerotherapy / Magnetic Resonance Imaging, Interventional / Vascular Malformations Type of study: Guideline / Qualitative_research Limits: Adolescent / Adult / Child / Female / Humans / Male / Middle aged Language: En Year: 2017 Type: Article