Placental Hypoxia During Early Pregnancy Causes Maternal Hypertension and Placental Insufficiency in the Hypoxic Guinea Pig Model.

Thompson, Loren P; Pence, Laramie; Pinkas, Gerald; Song, Hong; Telugu, Bhanu P

Thompson, Loren P; Pence, Laramie; Pinkas, Gerald; Song, Hong; Telugu, Bhanu P.

Affiliation

Thompson LP; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland, Baltimore, Maryland lthompson1@umm.edu.
Pence L; University of Maryland School of Medicine, Baltimore, Maryland.
Pinkas G; Animal Biosciences and Biotechnology Laboratory, USDA-ARS, Beltsville, Maryland.
Song H; Animal and Avian Science, University of Maryland, College Park, Maryland.
Telugu BP; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland, Baltimore, Maryland.

Biol Reprod ; 95(6): 128, 2016 12.

Article in En | MEDLINE | ID: mdl-27806942

Subject(s)

Hypertension, Pregnancy-Induced/etiology; Hypoxia/complications; Placenta/metabolism; Placental Insufficiency/etiology; Animals; Blood Pressure/physiology; Cell Proliferation/physiology; Disease Models, Animal; Female; Guinea Pigs; Hypertension, Pregnancy-Induced/metabolism; Hypertension, Pregnancy-Induced/physiopathology; Hypoxia/metabolism; Hypoxia/physiopathology; Keratin-7/metabolism; Organ Size/physiology; Placenta/physiopathology; Placental Insufficiency/metabolism; Placental Insufficiency/physiopathology; Placentation; Pregnancy; Proliferating Cell Nuclear Antigen/metabolism; Vascular Remodeling/physiology

Key words

animal model; hypoxia; maternal hypertension; placental insufficiency; pregnancy

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Placenta / Placental Insufficiency / Hypertension, Pregnancy-Induced / Hypoxia Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Pregnancy Language: En Year: 2016 Type: Article

Fulltext

XML

PubMed Links

Search on Google