Regulation of KCNQ/Kv7 family voltage-gated K<sup>+</sup> channels by lipids.

Taylor, Keenan C; Sanders, Charles R

Regulation of KCNQ/Kv7 family voltage-gated K⁺ channels by lipids.

Taylor, Keenan C; Sanders, Charles R.

Affiliation

Taylor KC; Department of Biochemistry, Vanderbilt University, Nashville, TN, USA; Center for Structural Biology, Vanderbilt University, Nashville, TN, USA.
Sanders CR; Department of Biochemistry, Vanderbilt University, Nashville, TN, USA; Center for Structural Biology, Vanderbilt University, Nashville, TN, USA; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: chuck.sanders@vanderbilt.edu.

Biochim Biophys Acta Biomembr ; 1859(4): 586-597, 2017 Apr.

Article in En | MEDLINE | ID: mdl-27818172

Subject(s)

Epilepsy, Benign Neonatal/metabolism; Hearing Loss, Bilateral/metabolism; KCNQ1 Potassium Channel/chemistry; Long QT Syndrome/metabolism; Membrane Lipids/chemistry; Amino Acid Sequence; Binding Sites; Cell Membrane/chemistry; Cell Membrane/metabolism; Epilepsy, Benign Neonatal/pathology; Fatty Acids, Unsaturated/chemistry; Fatty Acids, Unsaturated/metabolism; Hearing Loss, Bilateral/pathology; Humans; Hydrophobic and Hydrophilic Interactions; KCNQ1 Potassium Channel/deficiency; KCNQ1 Potassium Channel/metabolism; Long QT Syndrome/pathology; Membrane Lipids/metabolism; Models, Molecular; Phosphatidylinositol 4,5-Diphosphate/chemistry; Phosphatidylinositol 4,5-Diphosphate/metabolism; Protein Binding; Protein Isoforms/chemistry; Protein Isoforms/deficiency; Protein Isoforms/metabolism; Protein Structure, Secondary

Key words

Annular; Channel; KCNQ1; Kv7.1; Lipids; Membrane; PIP2; PUFA; Potassium; Voltage-gated

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Full text: 1 Database: MEDLINE Main subject: Long QT Syndrome / Epilepsy, Benign Neonatal / KCNQ1 Potassium Channel / Hearing Loss, Bilateral / Membrane Lipids Limits: Humans Language: En Year: 2017 Type: Article

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