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Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains.
Swanger, Sharon A; Chen, Wenjuan; Wells, Gordon; Burger, Pieter B; Tankovic, Anel; Bhattacharya, Subhrajit; Strong, Katie L; Hu, Chun; Kusumoto, Hirofumi; Zhang, Jing; Adams, David R; Millichap, John J; Petrovski, Slavé; Traynelis, Stephen F; Yuan, Hongjie.
Affiliation
  • Swanger SA; Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Chen W; Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Wells G; Department of Chemistry, Emory University, Atlanta, GA 30322, USA.
  • Burger PB; Department of Chemistry, Emory University, Atlanta, GA 30322, USA.
  • Tankovic A; Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Bhattacharya S; Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Strong KL; Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, USA; Department of Chemistry, Emory University, Atlanta, GA 30322, USA.
  • Hu C; Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Kusumoto H; Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Zhang J; Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Adams DR; Undiagnosed Diseases Network, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA.
  • Millichap JJ; Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine and Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.
  • Petrovski S; Department of Medicine, The University of Melbourne, Austin Health and Royal Melbourne Hospital, Melbourne, VIC 3050, Australia.
  • Traynelis SF; Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, USA; Center for Functional Evaluation of Rare Variants (CFERV), Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address: strayne@emory.edu.
  • Yuan H; Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, USA; Center for Functional Evaluation of Rare Variants (CFERV), Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address: hyuan@emory.edu.
Am J Hum Genet ; 99(6): 1261-1280, 2016 Dec 01.
Article in En | MEDLINE | ID: mdl-27839871
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Full text: 1 Database: MEDLINE Main subject: Receptors, N-Methyl-D-Aspartate Limits: Humans Language: En Year: 2016 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Receptors, N-Methyl-D-Aspartate Limits: Humans Language: En Year: 2016 Type: Article