Long-term outcome of percutaneous alcohol embolization combined with percutaneous vertebroplasty in aggressive vertebral hemangiomas with epidural extension.
Eur Radiol
; 27(7): 2860-2867, 2017 Jul.
Article
in En
| MEDLINE
| ID: mdl-27921158
ABSTRACT
OBJECTIVES:
To evaluate, on a long-term basis, the safety and effectiveness of percutaneous alcohol embolization (PAE) combined with percutaneous vertebroplasty (PVP) as a sole treatment for aggressive vertebral haemangiomas (AVHs) with epidural extension.METHODS:
From 1996 to 2015, 26 consecutive patients (15 women [58%] and 11 men; mean age 51.8 years [range 19-75 years]) underwent PAE combined with PVP (performed at day 15) for the treatment of 27 AVHs with epidural extension. Clinical outcome was evaluated with a mean delay of 88.3 ± 53.3 months (range 22-217 months). The primary endpoint was pain relief evaluated with a visual analogue scale (VAS).RESULTS:
Pre-procedure mean VAS score was 7.23 ± 1.3 and significantly improved at last follow-up (m = 3.11 ± 1.9; p < 0.001). Ten patients (38.5%) remained asymptomatic. Eighty-eight percent of the patients with neurosensory disorders had complete regression of these symptoms. Two of the three patients with motor deficit did not show any improvement. No major complication was recorded.CONCLUSIONS:
PAE combined with PVP is a minimally invasive safe and effective therapeutic approach for AVH with epidural involvement, even on long-term clinical outcome. This technique appears mainly effective for pain and neurosensory symptoms, but seems less effective for motor deficit relief. KEY POINTS ⢠Combination of PAE with PVP is a safe technique. ⢠PAE combined with PVP is an effective treatment for sensory symptoms. ⢠This strategy seems less effective in patients with motor deficits.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Spinal Neoplasms
/
Thoracic Vertebrae
/
Epidural Neoplasms
/
Chemoembolization, Therapeutic
/
Embolization, Therapeutic
/
Vertebroplasty
/
Hemangioma
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Year:
2017
Type:
Article