Comparative pharmacodynamic effects of two clopidogrel formulations under steady-state conditions in healthy Thai volunteersâ©.

Nakkam, Nontaya; Tiamkao, Somsak; Kanjanawart, Sirimas; Phunikhom, Kutcharin; Tiamkao, Siriporn; Vannaprasaht, Suda; Tassaneeyakul, Wongwiwat; Tassaneeyakul, Wichittra

Comparative pharmacodynamic effects of two clopidogrel formulations under steady-state conditions in healthy Thai volunteersâ©.

Nakkam, Nontaya; Tiamkao, Somsak; Kanjanawart, Sirimas; Phunikhom, Kutcharin; Tiamkao, Siriporn; Vannaprasaht, Suda; Tassaneeyakul, Wongwiwat; Tassaneeyakul, Wichittra.

Int J Clin Pharmacol Ther ; 55(2): 177-185, 2017 Feb.

Article in En | MEDLINE | ID: mdl-27936524

Subject(s)

Blood Platelets/drug effects; Drugs, Generic/pharmacokinetics; Platelet Aggregation Inhibitors/administration & dosage; Platelet Aggregation/drug effects; Purinergic P2Y Receptor Antagonists/administration & dosage; Ticlopidine/analogs & derivatives; Adult; Area Under Curve; Asian People; Blood Platelets/metabolism; Clopidogrel; Cross-Over Studies; Drug Compounding; Drugs, Generic/administration & dosage; Healthy Volunteers; Humans; Male; Platelet Aggregation Inhibitors/blood; Platelet Aggregation Inhibitors/pharmacokinetics; Platelet Function Tests; Purinergic P2Y Receptor Antagonists/blood; Purinergic P2Y Receptor Antagonists/pharmacokinetics; Receptors, Purinergic P2Y12/blood; Receptors, Purinergic P2Y12/drug effects; Thailand; Therapeutic Equivalency; Ticlopidine/administration & dosage; Ticlopidine/blood; Ticlopidine/pharmacokinetics; Young Adult

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Full text: 1 Database: MEDLINE Main subject: Blood Platelets / Ticlopidine / Platelet Aggregation Inhibitors / Platelet Aggregation / Drugs, Generic / Purinergic P2Y Receptor Antagonists Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Humans / Male Country/Region as subject: Asia Language: En Year: 2017 Type: Article

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