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Azaindoles as Zinc-Binding Small-Molecule Inhibitors of the JAMM Protease CSN5.
Altmann, Eva; Erbel, Paul; Renatus, Martin; Schaefer, Michael; Schlierf, Anita; Druet, Adelaide; Kieffer, Laurence; Sorge, Mickael; Pfister, Keith; Hassiepen, Ulrich; Jones, Matthew; Ruedisser, Simon; Ostermeier, Daniela; Martoglio, Bruno; Jefferson, Anne B; Quancard, Jean.
Affiliation
  • Altmann E; Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Erbel P; Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Renatus M; Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Schaefer M; Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Schlierf A; Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Druet A; Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Kieffer L; Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Sorge M; Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Pfister K; Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Hassiepen U; Novartis Institutes for BioMedical Research, 4560 Horton Street, Emeryville, CA, 94608-2916, USA.
  • Jones M; Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Ruedisser S; Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Ostermeier D; Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Martoglio B; Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Jefferson AB; Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Quancard J; Pharma Research and Early Development, Roche Innovation Center Basel, 4070, Basel, Switzerland.
Angew Chem Int Ed Engl ; 56(5): 1294-1297, 2017 01 24.
Article in En | MEDLINE | ID: mdl-27981705
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Full text: 1 Database: MEDLINE Main subject: Zinc / COP9 Signalosome Complex / Indoles Limits: Humans Language: En Year: 2017 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Zinc / COP9 Signalosome Complex / Indoles Limits: Humans Language: En Year: 2017 Type: Article