A bromodomain-DNA interaction facilitates acetylation-dependent bivalent nucleosome recognition by the BET protein BRDT.

Miller, Thomas C R; Simon, Bernd; Rybin, Vladimir; Grötsch, Helga; Curtet, Sandrine; Khochbin, Saadi; Carlomagno, Teresa; Müller, Christoph W

Miller, Thomas C R; Simon, Bernd; Rybin, Vladimir; Grötsch, Helga; Curtet, Sandrine; Khochbin, Saadi; Carlomagno, Teresa; Müller, Christoph W.

Affiliation

Miller TC; European Molecular Biology Laboratory (EMBL), Structural and Computational Biology Unit, Meyerhofstrasse 1, Heidelberg 69117, Germany.
Simon B; European Molecular Biology Laboratory (EMBL), Structural and Computational Biology Unit, Meyerhofstrasse 1, Heidelberg 69117, Germany.
Rybin V; European Molecular Biology Laboratory (EMBL), Structural and Computational Biology Unit, Meyerhofstrasse 1, Heidelberg 69117, Germany.
Grötsch H; European Molecular Biology Laboratory (EMBL), Structural and Computational Biology Unit, Meyerhofstrasse 1, Heidelberg 69117, Germany.
Curtet S; CNRS UMR 5309, INSERM, U1209, Université Grenoble Alpes, Institut Albert Bonniot, 38700 Grenoble, France.
Khochbin S; CNRS UMR 5309, INSERM, U1209, Université Grenoble Alpes, Institut Albert Bonniot, 38700 Grenoble, France.
Carlomagno T; European Molecular Biology Laboratory (EMBL), Structural and Computational Biology Unit, Meyerhofstrasse 1, Heidelberg 69117, Germany.
Müller CW; Leibniz University Hannover, Centre for Biomolecular Drug Research, D-30167 Hannover, Germany.

Nat Commun ; 7: 13855, 2016 12 19.

Article in En | MEDLINE | ID: mdl-27991587

Subject(s)

Nuclear Proteins/chemistry; Nucleosomes/chemistry; Acetylation; Amino Acid Sequence; Histones; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleosomes/metabolism; Protein Binding; Protein Domains; Protein Processing, Post-Translational; Protein Structure, Tertiary

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