Improvement of whole-cell transamination with Saccharomyces cerevisiae using metabolic engineering and cell pre-adaptation.

Weber, Nora; Gorwa-Grauslund, Marie; Carlquist, Magnus

Weber, Nora; Gorwa-Grauslund, Marie; Carlquist, Magnus.

Affiliation

Weber N; Division of Applied Microbiology, Department of Chemistry, Faculty of Engineering, Lund University, PO Box 124, 221 00, Lund, Sweden.
Gorwa-Grauslund M; Evolva SA, Duggingerstrasse 23, 4153, Reinach, Switzerland.
Carlquist M; Division of Applied Microbiology, Department of Chemistry, Faculty of Engineering, Lund University, PO Box 124, 221 00, Lund, Sweden.

Microb Cell Fact ; 16(1): 3, 2017 Jan 03.

Article in En | MEDLINE | ID: mdl-28049528

Subject(s)

Metabolic Engineering/methods; Saccharomyces cerevisiae/enzymology; Saccharomyces cerevisiae/genetics; Transaminases/metabolism; Capsicum/enzymology; Capsicum/genetics; Chromobacterium/enzymology; Chromobacterium/genetics; Ochrobactrum anthropi/enzymology; Ochrobactrum anthropi/genetics; Phenethylamines/metabolism; Saccharomyces cerevisiae/metabolism; Stereoisomerism; Transaminases/biosynthesis; Transaminases/genetics

Key words

Amine transaminase; Chiral amine; Co-substrate; Pyridoxal-5'-phosphate; Pyruvate decarboxylase; Whole-cell bioconversion; Yeast

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Full text: 1 Database: MEDLINE Main subject: Saccharomyces cerevisiae / Metabolic Engineering / Transaminases Language: En Year: 2017 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Saccharomyces cerevisiae / Metabolic Engineering / Transaminases Language: En Year: 2017 Type: Article