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Targeting TNFR2 with antagonistic antibodies inhibits proliferation of ovarian cancer cells and tumor-associated Tregs.
Torrey, Heather; Butterworth, John; Mera, Toshiyuki; Okubo, Yoshiaki; Wang, Limei; Baum, Danielle; Defusco, Audrey; Plager, Sara; Warden, Sarah; Huang, Daniel; Vanamee, Eva; Foster, Rosemary; Faustman, Denise L.
Affiliation
  • Torrey H; Immunobiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
  • Butterworth J; Immunobiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
  • Mera T; Immunobiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
  • Okubo Y; Immunobiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
  • Wang L; Immunobiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
  • Baum D; Immunobiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
  • Defusco A; Immunobiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
  • Plager S; Immunobiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
  • Warden S; Immunobiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
  • Huang D; Immunobiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
  • Vanamee E; Immunobiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
  • Foster R; Department of Obstetrics and Gynecology, Massachusetts General Hospital and Harvard Medical School, Vincent Center for Reproductive Biology, Boston, MA 02114, USA.
  • Faustman DL; Immunobiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA. faustman@helix.mgh.harvard.edu.
Sci Signal ; 10(462)2017 01 17.
Article in En | MEDLINE | ID: mdl-28096513
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Full text: 1 Database: MEDLINE Main subject: T-Lymphocytes, Regulatory / Receptors, Tumor Necrosis Factor, Type II / Cell Proliferation / Antibodies, Monoclonal Type of study: Risk_factors_studies Limits: Female / Humans Language: En Year: 2017 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: T-Lymphocytes, Regulatory / Receptors, Tumor Necrosis Factor, Type II / Cell Proliferation / Antibodies, Monoclonal Type of study: Risk_factors_studies Limits: Female / Humans Language: En Year: 2017 Type: Article