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RhoA knockout fibroblasts lose tumor-inhibitory capacity in vitro and promote tumor growth in vivo.
Alkasalias, Twana; Alexeyenko, Andrey; Hennig, Katharina; Danielsson, Frida; Lebbink, Robert Jan; Fielden, Matthew; Turunen, S Pauliina; Lehti, Kaisa; Kashuba, Vladimir; Madapura, Harsha S; Bozoky, Benedek; Lundberg, Emma; Balland, Martial; Guvén, Hayrettin; Klein, George; Gad, Annica K B; Pavlova, Tatiana.
Affiliation
  • Alkasalias T; Department of Microbiology, Tumour, and Cell Biology, Karolinska Institutet, 17177 Stockholm, Sweden.
  • Alexeyenko A; Department of Biology, College of Science, Salahaddin University, 44002, Irbil, Kurdistan-Iraq.
  • Hennig K; Department of Microbiology, Tumour, and Cell Biology, Karolinska Institutet, 17177 Stockholm, Sweden.
  • Danielsson F; National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Karolinska Institute, 17177 Stockholm, Sweden.
  • Lebbink RJ; Laboratoire Interdisciplinaire de Physique, Université Joseph Fourier (Grenoble 1), 38402 Saint Martin d'Hères Cedex 9, France.
  • Fielden M; National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Karolinska Institute, 17177 Stockholm, Sweden.
  • Turunen SP; Department of Medical Microbiology, University Medical Centre Utrecht, 3584 CX Utrecht, The Netherlands.
  • Lehti K; Department of Applied Physics, Nanostructure Physics, Kungliga Tekniska Högskolan Royal Institute of Technology, Albanova University Center, 106 91 Stockholm, Sweden.
  • Kashuba V; Department of Microbiology, Tumour, and Cell Biology, Karolinska Institutet, 17177 Stockholm, Sweden.
  • Madapura HS; Department of Microbiology, Tumour, and Cell Biology, Karolinska Institutet, 17177 Stockholm, Sweden.
  • Bozoky B; Research Programmes Unit, Genome-Scale Biology, University of Helsinki, Finnish Cancer Institute, F1-00014 Helsinki, Finland.
  • Lundberg E; Department of Microbiology, Tumour, and Cell Biology, Karolinska Institutet, 17177 Stockholm, Sweden.
  • Balland M; Department of Molecular Oncogenetics, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, 01004 Kiev, Ukraine.
  • Guvén H; Department of Microbiology, Tumour, and Cell Biology, Karolinska Institutet, 17177 Stockholm, Sweden.
  • Klein G; Department of Microbiology, Tumour, and Cell Biology, Karolinska Institutet, 17177 Stockholm, Sweden.
  • Gad AK; Cell Profiling Facility, Science for Life Laboratory, Kungliga Tekniska Högskolan Royal Institute of Technology, 17177 Stockholm, Sweden.
  • Pavlova T; Laboratoire Interdisciplinaire de Physique, Université Joseph Fourier (Grenoble 1), 38402 Saint Martin d'Hères Cedex 9, France.
Proc Natl Acad Sci U S A ; 114(8): E1413-E1421, 2017 02 21.
Article in En | MEDLINE | ID: mdl-28174275
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Full text: 1 Database: MEDLINE Main subject: RhoA GTP-Binding Protein / Cell Proliferation / Cancer-Associated Fibroblasts / Neoplasms Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Year: 2017 Type: Article
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Full text: 1 Database: MEDLINE Main subject: RhoA GTP-Binding Protein / Cell Proliferation / Cancer-Associated Fibroblasts / Neoplasms Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Year: 2017 Type: Article