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Blockage of Glyoxalase I Inhibits Colorectal Tumorigenesis and Tumor Growth via Upregulation of STAT1, p53, and Bax and Downregulation of c-Myc and Bcl-2.
Chen, Yuan; Fang, Lei; Zhang, Jiali; Li, Gefei; Ma, Mengni; Li, Changxi; Lyu, Jianxin; Meng, Qing H.
Affiliation
  • Chen Y; Key Laboratory of Laboratory Medicine, Ministry of Education of China, Zhejiang Provincial Key Laboratory of Medical Genetics, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou 325035, China. 15057766065@163.com.
  • Fang L; Key Laboratory of Laboratory Medicine, Ministry of Education of China, Zhejiang Provincial Key Laboratory of Medical Genetics, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou 325035, China. 15158652395@163.com.
  • Zhang J; Key Laboratory of Laboratory Medicine, Ministry of Education of China, Zhejiang Provincial Key Laboratory of Medical Genetics, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou 325035, China. 15057765887@163.com.
  • Li G; Key Laboratory of Laboratory Medicine, Ministry of Education of China, Zhejiang Provincial Key Laboratory of Medical Genetics, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou 325035, China. ligefei1992@163.com.
  • Ma M; Key Laboratory of Laboratory Medicine, Ministry of Education of China, Zhejiang Provincial Key Laboratory of Medical Genetics, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou 325035, China. mamengni123@163.com.
  • Li C; Key Laboratory of Laboratory Medicine, Ministry of Education of China, Zhejiang Provincial Key Laboratory of Medical Genetics, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou 325035, China. 15967411311@163.com.
  • Lyu J; Key Laboratory of Laboratory Medicine, Ministry of Education of China, Zhejiang Provincial Key Laboratory of Medical Genetics, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou 325035, China. ljx@wmu.edu.cn.
  • Meng QH; Key Laboratory of Laboratory Medicine, Ministry of Education of China, Zhejiang Provincial Key Laboratory of Medical Genetics, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou 325035, China. qhmeng@mdanderson.org.
Int J Mol Sci ; 18(3)2017 Mar 09.
Article in En | MEDLINE | ID: mdl-28282916
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Full text: 1 Database: MEDLINE Main subject: Colorectal Neoplasms / Tumor Suppressor Protein p53 / Proto-Oncogene Proteins c-myc / Proto-Oncogene Proteins c-bcl-2 / STAT1 Transcription Factor / Bcl-2-Associated X Protein / Lactoylglutathione Lyase Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Year: 2017 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Colorectal Neoplasms / Tumor Suppressor Protein p53 / Proto-Oncogene Proteins c-myc / Proto-Oncogene Proteins c-bcl-2 / STAT1 Transcription Factor / Bcl-2-Associated X Protein / Lactoylglutathione Lyase Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Year: 2017 Type: Article