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Anaphylactic reaction to tranexamic acid in an adolescent undergoing posterior spinal fusion.
Chiem, Jennifer; Ivanova, Iskra; Parker, Andrew; Krengel, Walter; Jimenez, Nathalia.
Affiliation
  • Chiem J; Department of Anesthesiology and Pain Medicine, Seattle Children's Hospital, University of Washington, Seattle, WA, USA.
  • Ivanova I; Department of Anesthesiology and Pain Medicine, Seattle Children's Hospital, University of Washington, Seattle, WA, USA.
  • Parker A; Department of Immunology, Seattle Children's Hospital, University of Washington, Seattle, WA, USA.
  • Krengel W; Department of Orthopedic Surgery, Seattle Children's Hospital, University of Washington, Seattle, WA, USA.
  • Jimenez N; Department of Anesthesiology and Pain Medicine, Seattle Children's Hospital, University of Washington, Seattle, WA, USA.
Paediatr Anaesth ; 27(7): 774-775, 2017 Jul.
Article in En | MEDLINE | ID: mdl-28321954
ABSTRACT
Tranexamic acid is an anti-fibrinolytic agent frequently used in pediatric surgery. Common side effects include nausea, flushing, and headache, but in rare instances, it may produce anaphylaxis; with only one previously reported case in a 72-year-old man. We report a case of a delayed anaphylactic reaction in a pediatric patient undergoing posterior spine fusion; and discuss the intraoperative management of the acute event, immunologic confirmation, and subsequent anesthetic approach.
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Full text: 1 Database: MEDLINE Main subject: Spinal Fusion / Tranexamic Acid / Anaphylaxis / Intraoperative Complications / Antifibrinolytic Agents Limits: Adolescent / Humans / Male Language: En Year: 2017 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Spinal Fusion / Tranexamic Acid / Anaphylaxis / Intraoperative Complications / Antifibrinolytic Agents Limits: Adolescent / Humans / Male Language: En Year: 2017 Type: Article