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A single trophectoderm biopsy at blastocyst stage is mathematically unable to determine embryo ploidy accurately enough for clinical use.
Gleicher, Norbert; Metzger, Jacob; Croft, Gist; Kushnir, Vitaly A; Albertini, David F; Barad, David H.
Affiliation
  • Gleicher N; The Center for Human Reproduction, 21 East 69th Street, New York, NY, 10021, USA. ngleicher@thechr.com.
  • Metzger J; Foundation for Reproductive Medicine, New York, NY, 10022, USA. ngleicher@thechr.com.
  • Croft G; Laboratory of Stem Cell Biology and Molecular Embryology, The Rockefeller University, New York, NY, 10065, USA. ngleicher@thechr.com.
  • Kushnir VA; Department of Obstetrics and Gynecology, University of Vienna School of Medicine, 1090, Vienna, Austria. ngleicher@thechr.com.
  • Albertini DF; Center for Studies in Physics and Biology, The Rockefeller University, New York, NY, 10065, USA.
  • Barad DH; Laboratory of Stem Cell Biology and Molecular Embryology, The Rockefeller University, New York, NY, 10065, USA.
Reprod Biol Endocrinol ; 15(1): 33, 2017 Apr 27.
Article in En | MEDLINE | ID: mdl-28449669
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Full text: 1 Database: MEDLINE Main subject: Ploidies / Trophoblasts / Blastocyst / Cleavage Stage, Ovum / Preimplantation Diagnosis / Ectoderm Type of study: Diagnostic_studies / Evaluation_studies / Prognostic_studies Limits: Female / Humans / Pregnancy Language: En Year: 2017 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Ploidies / Trophoblasts / Blastocyst / Cleavage Stage, Ovum / Preimplantation Diagnosis / Ectoderm Type of study: Diagnostic_studies / Evaluation_studies / Prognostic_studies Limits: Female / Humans / Pregnancy Language: En Year: 2017 Type: Article