ADAM Proteins/metabolism; Blood Platelets/enzymology; Cell Membrane/enzymology; Epidermal Growth Factor/metabolism; ErbB Receptors/agonists; Platelet Activation; Protein Precursors/metabolism; ADAM Proteins/antagonists & inhibitors; ADAM Proteins/chemistry; ADAM Proteins/genetics; Animals; Blood Platelets/metabolism; CHO Cells; Cell Line, Tumor; Cell Membrane/metabolism; Cricetulus; Epidermal Growth Factor/chemistry; Epidermal Growth Factor/genetics; ErbB Receptors/genetics; ErbB Receptors/metabolism; Humans; Hydrolases/genetics; Hydrolases/metabolism; Kinetics; Molecular Weight; Oligopeptides/pharmacology; Protease Inhibitors/pharmacology; Protein Interaction Domains and Motifs; Protein Precursors/chemistry; Protein Precursors/genetics; Protein Processing, Post-Translational/drug effects; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Proteolysis/drug effects; Recombinant Proteins/chemistry; Recombinant Proteins/metabolism; Solubility

ADAM; epidermal growth factor (EGF); growth factor; metalloprotease; platelet