Fgf10 and Sox9 are essential for the establishment of distal progenitor cells during mouse salivary gland development.

Chatzeli, Lemonia; Gaete, Marcia; Tucker, Abigail S

Chatzeli, Lemonia; Gaete, Marcia; Tucker, Abigail S.

Affiliation

Chatzeli L; Centre for Craniofacial and Regenerative Biology, Department of Craniofacial Development & Stem Cell Biology, King's College London, London SE1 9RT, UK.
Gaete M; Centre for Craniofacial and Regenerative Biology, Department of Craniofacial Development & Stem Cell Biology, King's College London, London SE1 9RT, UK.
Tucker AS; Department of Anatomy, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile.

Development ; 144(12): 2294-2305, 2017 06 15.

Article in En | MEDLINE | ID: mdl-28506998

Subject(s)

Fibroblast Growth Factor 10/metabolism; SOX9 Transcription Factor/metabolism; Salivary Glands/embryology; Salivary Glands/metabolism; Animals; Collagen Type II/genetics; Collagen Type II/metabolism; Embryonic Stem Cells/cytology; Embryonic Stem Cells/metabolism; Epithelial Cells/cytology; Epithelial Cells/metabolism; Female; Fibroblast Growth Factor 10/genetics; Gene Expression Regulation, Developmental; MAP Kinase Signaling System; Male; Mice; Mice, Knockout; Models, Biological; Morphogenesis/physiology; Pregnancy; SOX9 Transcription Factor/antagonists & inhibitors; SOX9 Transcription Factor/genetics; Salivary Glands/cytology; Signal Transduction; Submandibular Gland/cytology; Submandibular Gland/embryology; Submandibular Gland/metabolism

Key words

Branching morphogenesis; Epithelial progenitors; Fgf signalling; Salivary glands; Sox9

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Full text: 1 Database: MEDLINE Main subject: Salivary Glands / Fibroblast Growth Factor 10 / SOX9 Transcription Factor Type of study: Prognostic_studies Limits: Animals / Pregnancy Language: En Year: 2017 Type: Article

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