Parasitic Protozoa and Interactions with the Host Intestinal Microbiota.
Infect Immun
; 85(8)2017 08.
Article
in En
| MEDLINE
| ID: mdl-28584161
ABSTRACT
Parasitic protozoan infections represent a major health burden in the developing world and contribute significantly to morbidity and mortality. These infections are often associated with considerable variability in clinical presentation. An emerging body of work suggests that the intestinal microbiota may help to explain some of these differences in disease expression. The objective of this minireview is to synthesize recent progress in this rapidly advancing field. Studies of humans and animals and in vitro studies of the contribution of the intestinal microbiota to infectious disease are discussed. We hope to provide an understanding of the human-protozoal pathogen-microbiome interaction and to speculate on how that might be leveraged for treatment.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Parasites
/
Gastrointestinal Microbiome
/
Host-Parasite Interactions
Limits:
Animals
/
Humans
Language:
En
Year:
2017
Type:
Article