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IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment.
Nirschl, Christopher J; Suárez-Fariñas, Mayte; Izar, Benjamin; Prakadan, Sanjay; Dannenfelser, Ruth; Tirosh, Itay; Liu, Yong; Zhu, Qian; Devi, K Sanjana P; Carroll, Shaina L; Chau, David; Rezaee, Melika; Kim, Tae-Gyun; Huang, Ruiqi; Fuentes-Duculan, Judilyn; Song-Zhao, George X; Gulati, Nicholas; Lowes, Michelle A; King, Sandra L; Quintana, Francisco J; Lee, Young-Suk; Krueger, James G; Sarin, Kavita Y; Yoon, Charles H; Garraway, Levi; Regev, Aviv; Shalek, Alex K; Troyanskaya, Olga; Anandasabapathy, Niroshana.
Affiliation
  • Nirschl CJ; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Suárez-Fariñas M; Department of Dermatology, Mount Sinai School of Medicine, NY, NY 10029, USA; Department of Genetics and Genomics Sciences Mount Sinai School of Medicine, NY, NY 10029 USA; Population Health Science and Policy, Mount Sinai School of Medicine, NY, NY 10029, USA.
  • Izar B; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Center for Cancer Precision Medicine, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Prakadan S; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Institute for Medical Engineering and Science and Department of Chemistry, MIT, Cambridge, MA 02139, USA; Ragon Institute of MIT, Harvard, and MGH, Cambridge, MA 02139, USA.
  • Dannenfelser R; Department of Computer Science, Princeton University, Princeton, NJ 08540, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08540, USA.
  • Tirosh I; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Liu Y; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Zhu Q; Department of Computer Science, Princeton University, Princeton, NJ 08540, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08540, USA.
  • Devi KSP; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Carroll SL; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Institute for Medical Engineering and Science and Department of Chemistry, MIT, Cambridge, MA 02139, USA; Ragon Institute of MIT, Harvard, and MGH, Cambridge, MA 02139, USA.
  • Chau D; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Rezaee M; Department of Dermatology, Stanford University, Stanford, CA 94305, USA.
  • Kim TG; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Huang R; Department of Genetics and Genomics Sciences Mount Sinai School of Medicine, NY, NY 10029 USA.
  • Fuentes-Duculan J; Laboratory for Investigative Dermatology, Rockefeller University. New York, NY 10065, USA.
  • Song-Zhao GX; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Gulati N; Laboratory for Investigative Dermatology, Rockefeller University. New York, NY 10065, USA.
  • Lowes MA; Laboratory for Investigative Dermatology, Rockefeller University. New York, NY 10065, USA.
  • King SL; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Quintana FJ; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Neurology, Brigham and Women's Hospital, Boston, MA 02458, USA.
  • Lee YS; Department of Computer Science, Princeton University, Princeton, NJ 08540, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08540, USA.
  • Krueger JG; Laboratory for Investigative Dermatology, Rockefeller University. New York, NY 10065, USA.
  • Sarin KY; Department of Dermatology, Stanford University, Stanford, CA 94305, USA.
  • Yoon CH; Department of Surgical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Department of Surgical Oncology, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Garraway L; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Center for Cancer Precision Medicine, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Ludwig Center at Harvard, Boston, MA 0
  • Regev A; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA; Department of Biology and Koch Institute, MIT, Boston, MA 02142, USA.
  • Shalek AK; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Institute for Medical Engineering and Science and Department of Chemistry, MIT, Cambridge, MA 02139, USA; Ragon Institute of MIT, Harvard, and MGH, Cambridge, MA 02139, USA; Division of Health Science & Technology, Harvard Medical Sch
  • Troyanskaya O; Department of Computer Science, Princeton University, Princeton, NJ 08540, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08540, USA; Simons Center for Data Analysis, Simons Foundation, New York, NY 10010, USA.
  • Anandasabapathy N; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Cancer Immunology and Melanoma, Harvard Cancer Center, Dana Farber Cancer Center, Boston, MA 02215, USA; Harvard Stem Cell Institute, Boston, MA 02115, USA. Electronic address: nanandasabapathy@pa
Cell ; 170(1): 127-141.e15, 2017 Jun 29.
Article in En | MEDLINE | ID: mdl-28666115
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Full text: 1 Database: MEDLINE Main subject: Skin Neoplasms / Monocytes / Interferon-gamma / Suppressor of Cytokine Signaling Proteins / Tumor Microenvironment / Melanoma / Neoplasm Metastasis Limits: Animals / Humans Language: En Year: 2017 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Skin Neoplasms / Monocytes / Interferon-gamma / Suppressor of Cytokine Signaling Proteins / Tumor Microenvironment / Melanoma / Neoplasm Metastasis Limits: Animals / Humans Language: En Year: 2017 Type: Article