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A membrane-anchored aptamer sensor for probing IFNγ secretion by single cells.
Qiu, Liping; Wimmers, Florian; Weiden, Jorieke; Heus, Hans A; Tel, Jurjen; Figdor, Carl G.
Affiliation
  • Qiu L; Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China.
Chem Commun (Camb) ; 53(57): 8066-8069, 2017 Jul 13.
Article in En | MEDLINE | ID: mdl-28675396
Insight into the behavior of individual immune cells, in particular cytokine secretion, will contribute to a more fundamental understanding of the immune system. In this work, we have developed a cell membrane-anchored sensor for the detection of cytokines secreted by single cells using a combination of aptamer-based sensors and droplet microfluidics.
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Full text: 1 Database: MEDLINE Main subject: T-Lymphocytes / Biosensing Techniques / Interferon-gamma / Microfluidic Analytical Techniques / Aptamers, Nucleotide Limits: Humans Language: En Year: 2017 Type: Article
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Full text: 1 Database: MEDLINE Main subject: T-Lymphocytes / Biosensing Techniques / Interferon-gamma / Microfluidic Analytical Techniques / Aptamers, Nucleotide Limits: Humans Language: En Year: 2017 Type: Article