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Safety and efficacy of anti-influenza drugs, intravenous peramivir against influenza virus infection in elderly patients with underlying disease.
Takamatsu, Kazufumi; Marumo, Satoshi; Fukui, Motonari; Hata, Atsuko.
Affiliation
  • Takamatsu K; Department of Respiratory Medicine, Tazuke Kofukai Medical Research Institute Kitano Hospital, Japan.
  • Marumo S; Department of Respiratory Medicine, Tazuke Kofukai Medical Research Institute Kitano Hospital, Japan; Department of Infectious Diseases, Tazuke Kofukai Medical Research Institute Kitano Hospital, Japan.
  • Fukui M; Department of Respiratory Medicine, Tazuke Kofukai Medical Research Institute Kitano Hospital, Japan.
  • Hata A; Department of Pediatrics, Tazuke Kofukai Medical Research Institute Kitano Hospital, Japan; Department of Infectious Diseases, Tazuke Kofukai Medical Research Institute Kitano Hospital, Japan. Electronic address: a-hata@kitano-hp.or.jp.
J Microbiol Immunol Infect ; 50(4): 541-544, 2017 Aug.
Article in En | MEDLINE | ID: mdl-28720319
ABSTRACT
We retrospectively analyzed data of 38 elderly patients, each with an underlying disease, to evaluate peramivir safety and efficacy. Six patients (15.8%) experienced adverse events, all tolerated. Median time from administration until the return to normal temperatures was 31.5 h (95% CI 22.4-40.6). Results confirm intravenous peramivir's usefulness.
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Full text: 1 Database: MEDLINE Main subject: Antiviral Agents / Cyclopentanes / Influenza, Human / Guanidines Type of study: Observational_studies / Risk_factors_studies Limits: Aged / Aged80 / Female / Humans / Male Language: En Year: 2017 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Antiviral Agents / Cyclopentanes / Influenza, Human / Guanidines Type of study: Observational_studies / Risk_factors_studies Limits: Aged / Aged80 / Female / Humans / Male Language: En Year: 2017 Type: Article