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Structural Determinants for the Selectivity of the Positive KCa3.1 Gating Modulator 5-Methylnaphtho[2,1-d]oxazol-2-amine (SKA-121).
Brown, Brandon M; Shim, Heesung; Zhang, Miao; Yarov-Yarovoy, Vladimir; Wulff, Heike.
Affiliation
  • Brown BM; Department of Pharmacology (B.M.B., H.S., H.W.), Department of Physiology and Membrane Biology (V.Y.-Y.), School of Medicine, and Department of Chemistry (H.S.), University of California, Davis, California; and Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharma
  • Shim H; Department of Pharmacology (B.M.B., H.S., H.W.), Department of Physiology and Membrane Biology (V.Y.-Y.), School of Medicine, and Department of Chemistry (H.S.), University of California, Davis, California; and Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharma
  • Zhang M; Department of Pharmacology (B.M.B., H.S., H.W.), Department of Physiology and Membrane Biology (V.Y.-Y.), School of Medicine, and Department of Chemistry (H.S.), University of California, Davis, California; and Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharma
  • Yarov-Yarovoy V; Department of Pharmacology (B.M.B., H.S., H.W.), Department of Physiology and Membrane Biology (V.Y.-Y.), School of Medicine, and Department of Chemistry (H.S.), University of California, Davis, California; and Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharma
  • Wulff H; Department of Pharmacology (B.M.B., H.S., H.W.), Department of Physiology and Membrane Biology (V.Y.-Y.), School of Medicine, and Department of Chemistry (H.S.), University of California, Davis, California; and Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharma
Mol Pharmacol ; 92(4): 469-480, 2017 10.
Article in En | MEDLINE | ID: mdl-28760780

Full text: 1 Database: MEDLINE Main subject: Oxazoles / Ion Channel Gating / Intermediate-Conductance Calcium-Activated Potassium Channels Limits: Animals / Humans Language: En Year: 2017 Type: Article

Full text: 1 Database: MEDLINE Main subject: Oxazoles / Ion Channel Gating / Intermediate-Conductance Calcium-Activated Potassium Channels Limits: Animals / Humans Language: En Year: 2017 Type: Article