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Palmitoylation-dependent activation of MC1R prevents melanomagenesis.
Chen, Shuyang; Zhu, Bo; Yin, Chengqian; Liu, Wei; Han, Changpeng; Chen, Baoen; Liu, Tongzheng; Li, Xin; Chen, Xiang; Li, Chunying; Hu, Limin; Zhou, Jun; Xu, Zhi-Xiang; Gao, Xiumei; Wu, Xu; Goding, Colin R; Cui, Rutao.
Affiliation
  • Chen S; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts 02118, USA.
  • Zhu B; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts 02118, USA.
  • Yin C; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts 02118, USA.
  • Liu W; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts 02118, USA.
  • Han C; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts 02118, USA.
  • Chen B; Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA.
  • Liu T; Jinan University Institute of Tumor Pharmacology, Guangzhou, Guangdong 510632, China.
  • Li X; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts 02118, USA.
  • Chen X; Hunan Key Laboratory of Skin Cancer and Psoriasis/Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
  • Li C; Department of Dermatology, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi 710000, China.
  • Hu L; Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China.
  • Zhou J; State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin 300071, China.
  • Xu ZX; Division of Hematology and Oncology, Department of Medicine, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.
  • Gao X; Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China.
  • Wu X; Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA.
  • Goding CR; Ludwig Institute for Cancer Research, University of Oxford, Headington, Oxford OX3 7DQ, UK.
  • Cui R; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts 02118, USA.
Nature ; 549(7672): 399-403, 2017 09 21.
Article in En | MEDLINE | ID: mdl-28869973
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Full text: 1 Database: MEDLINE Main subject: Pigmentation / Cell Transformation, Neoplastic / Receptor, Melanocortin, Type 1 / Lipoylation / Melanoma Limits: Animals / Female / Humans / Male Language: En Year: 2017 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Pigmentation / Cell Transformation, Neoplastic / Receptor, Melanocortin, Type 1 / Lipoylation / Melanoma Limits: Animals / Female / Humans / Male Language: En Year: 2017 Type: Article