ASFA Category IV becomes Category I: Idiopathic thrombotic thrombocytopenic purpura in a patient with presumed gemcitabine-induced thrombotic microangiopathy.
J Clin Apher
; 33(3): 423-426, 2018 Jun.
Article
in En
| MEDLINE
| ID: mdl-28940604
ABSTRACT
In the implementation of American Society for Apheresis national guidelines, the decision for therapeutic plasma exchange may be confounded by a clinical presentation that fits both a Category I and IV designation. We report the case of a 45-year-old female who presented with concern for a Category IV disorder, gemcitabine-induced thrombotic microangiopathy, and was ultimately diagnosed with a Category I disorder, idiopathic thrombotic thrombocytopenic purpura. This case highlights the importance of ruling out idiopathic TTP by a thorough evaluation for ADAMTS13 activity and inhibitor, even when an alternate thrombotic microangiopathy diagnosis may be likely.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Purpura, Thrombotic Thrombocytopenic
/
Deoxycytidine
/
Thrombotic Microangiopathies
Type of study:
Diagnostic_studies
/
Guideline
/
Prognostic_studies
Limits:
Female
/
Humans
/
Middle aged
Language:
En
Year:
2018
Type:
Article