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Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication.
Kuss-Duerkop, Sharon K; Wang, Juan; Mena, Ignacio; White, Kris; Metreveli, Giorgi; Sakthivel, Ramanavelan; Mata, Miguel A; Muñoz-Moreno, Raquel; Chen, Xiang; Krammer, Florian; Diamond, Michael S; Chen, Zhijian J; García-Sastre, Adolfo; Fontoura, Beatriz M A.
Affiliation
  • Kuss-Duerkop SK; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
  • Wang J; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
  • Mena I; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
  • White K; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
  • Metreveli G; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
  • Sakthivel R; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
  • Mata MA; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
  • Muñoz-Moreno R; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
  • Chen X; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
  • Krammer F; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
  • Diamond MS; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
  • Chen ZJ; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America.
  • García-Sastre A; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
  • Fontoura BMA; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
PLoS Pathog ; 13(9): e1006635, 2017 Sep.
Article in En | MEDLINE | ID: mdl-28953980
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Full text: 1 Database: MEDLINE Main subject: Orthomyxoviridae / Virus Replication / Signal Transduction / Multiprotein Complexes / Proto-Oncogene Proteins c-akt / TOR Serine-Threonine Kinases Type of study: Prognostic_studies Limits: Humans Language: En Year: 2017 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Orthomyxoviridae / Virus Replication / Signal Transduction / Multiprotein Complexes / Proto-Oncogene Proteins c-akt / TOR Serine-Threonine Kinases Type of study: Prognostic_studies Limits: Humans Language: En Year: 2017 Type: Article