NeuBtracker-imaging neurobehavioral dynamics in freely behaving fish.
Nat Methods
; 14(11): 1079-1082, 2017 Nov.
Article
in En
| MEDLINE
| ID: mdl-28967889
ABSTRACT
A long-standing objective in neuroscience has been to image distributed neuronal activity in freely behaving animals. Here we introduce NeuBtracker, a tracking microscope for simultaneous imaging of neuronal activity and behavior of freely swimming fluorescent reporter fish. We showcase the value of NeuBtracker for screening neurostimulants with respect to their combined neuronal and behavioral effects and for determining spontaneous and stimulus-induced spatiotemporal patterns of neuronal activation during naturalistic behavior.
Full text:
1
Database:
MEDLINE
Main subject:
Behavior, Animal
/
Fishes
Limits:
Animals
Language:
En
Year:
2017
Type:
Article