Exploration of the expeditious potential of Pseudomonas fluorescens lipase in the kinetic resolution of racemic intermediates and its validation through molecular docking.

Soni, Surbhi; Dwivedee, Bharat P; Sharma, Vishnu K; Patel, Gopal; Banerjee, Uttam C

Soni, Surbhi; Dwivedee, Bharat P; Sharma, Vishnu K; Patel, Gopal; Banerjee, Uttam C.

Affiliation

Soni S; Department of Biotechnology, National Institute of Pharmaceutical Education and Research, Punjab, India.
Dwivedee BP; Department of Pharmaceutical Technology (Biotechnology), National Institute of Pharmaceutical Education and Research, Punjab, India.
Sharma VK; Department of Pharmacoinformatics, National Institute of Pharmaceutical Education and Research, Punjab, India.
Patel G; Department of Pharmaceutical Technology (Biotechnology), National Institute of Pharmaceutical Education and Research, Punjab, India.
Banerjee UC; Department of Pharmaceutical Technology (Biotechnology), National Institute of Pharmaceutical Education and Research, Punjab, India.

Chirality ; 30(1): 85-94, 2018 Jan.

Article in En | MEDLINE | ID: mdl-29064594

Subject(s)

Hexanes/chemistry; Lipase/chemistry; Pseudomonas fluorescens/chemistry; Solvents/chemistry; Acylation; Biocatalysis; Kinetics; Molecular Docking Simulation; Stereoisomerism

Key words

biocatalysis; chemoenzymatic synthesis; enantiomeric excess; enantioselectivity; ß-aryloxyalcohols

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Full text: 1 Database: MEDLINE Main subject: Solvents / Pseudomonas fluorescens / Hexanes / Lipase Language: En Year: 2018 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Solvents / Pseudomonas fluorescens / Hexanes / Lipase Language: En Year: 2018 Type: Article