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Panax quinquefolium saponin inhibits endoplasmic reticulum stress-induced apoptosis and the associated inflammatory response in chondrocytes and attenuates the progression of osteoarthritis in rat.
Xie, Jun-Jun; Chen, Jian; Guo, Shi-Kun; Gu, Yun-Tao; Yan, Ying-Zhao; Guo, Wei-Jun; Yao, Cheng-Lun; Jin, Meng-Yun; Xie, Cheng-Long; Wang, Xiang; Wang, Xiang-Yang; Chen, Long.
Affiliation
  • Xie JJ; School of Pharmaceutical Sciences, Key Laboratory of Biotechnology and Pharmaceutical Engineering, Wenzhou Medical University, Wenzhou, Zhejiang, 325027, People's Republic of China.
  • Chen J; Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University，Wenzhou, 325027, People's Republic of China.
  • Guo SK; Department of Postgraduate Education, Wenzhou Medical University, Wenzhou, 325027, People's Republic of China.
  • Gu YT; Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University，Wenzhou, 325027, People's Republic of China.
  • Yan YZ; Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University，Wenzhou, 325027, People's Republic of China.
  • Guo WJ; Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University，Wenzhou, 325027, People's Republic of China.
  • Yao CL; Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University，Wenzhou, 325027, People's Republic of China.
  • Jin MY; School of Pharmaceutical Sciences, Key Laboratory of Biotechnology and Pharmaceutical Engineering, Wenzhou Medical University, Wenzhou, Zhejiang, 325027, People's Republic of China.
  • Xie CL; Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University，Wenzhou, 325027, People's Republic of China.
  • Wang X; North Sichuan Medical College, Nanchong, 637000, People's Republic of China.
  • Wang XY; Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University，Wenzhou, 325027, People's Republic of China. Electronic address: xiangyangwang@wmu.edu.cn.
  • Chen L; Department of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University，Wenzhou, 325027, People's Republic of China. Electronic address: cl@wzhealth.com.
Biomed Pharmacother ; 97: 886-894, 2018 Jan.
Article in En | MEDLINE | ID: mdl-29136765
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Full text: 1 Database: MEDLINE Main subject: Osteoarthritis / Arthritis, Experimental / Saponins / Endoplasmic Reticulum Stress Type of study: Risk_factors_studies Limits: Animals Language: En Year: 2018 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Osteoarthritis / Arthritis, Experimental / Saponins / Endoplasmic Reticulum Stress Type of study: Risk_factors_studies Limits: Animals Language: En Year: 2018 Type: Article