Optimization of a Protease Activated Probe for Optical Surgical Navigation.

Yim, Joshua J; Tholen, Martina; Klaassen, Alwin; Sorger, Jonathan; Bogyo, Matthew

Yim, Joshua J; Tholen, Martina; Klaassen, Alwin; Sorger, Jonathan; Bogyo, Matthew.

Affiliation

Klaassen A; Intuitive Surgical Inc. , 1020 Kifer Road , Sunnyvale , California 94086 , United States.
Sorger J; Intuitive Surgical Inc. , 1020 Kifer Road , Sunnyvale , California 94086 , United States.

Mol Pharm ; 15(3): 750-758, 2018 03 05.

Article in En | MEDLINE | ID: mdl-29172524

Subject(s)

Contrast Media/metabolism; Mammary Neoplasms, Experimental/diagnostic imaging; Neoplasms/diagnostic imaging; Peptide Hydrolases/metabolism; Video-Assisted Surgery/methods; Animals; Cell Line, Tumor/transplantation; Contrast Media/administration & dosage; Contrast Media/chemistry; Female; Fluorescent Dyes/administration & dosage; Fluorescent Dyes/chemistry; Fluorescent Dyes/metabolism; Indocyanine Green/administration & dosage; Indocyanine Green/chemistry; Indocyanine Green/metabolism; Mammary Neoplasms, Experimental/surgery; Mice; Mice, Inbred BALB C; Molecular Imaging/methods; Neoplasms/pathology; Neoplasms/surgery

Key words

fluorescence guided surgery; fluorescently quenched probes; optical contrast agents

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Full text: 1 Database: MEDLINE Main subject: Peptide Hydrolases / Contrast Media / Video-Assisted Surgery / Mammary Neoplasms, Experimental / Neoplasms Limits: Animals Language: En Year: 2018 Type: Article

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