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DPP-4 inhibition with linagliptin ameliorates the progression of premature aging in klotho-/- mice.
Hasegawa, Yu; Hayashi, Kenyu; Takemoto, Yushin; Cheng, Cao; Takane, Koki; Lin, Bowen; Komohara, Yoshihiro; Kim-Mitsuyama, Shokei.
Affiliation
  • Hasegawa Y; Department of Pharmacology and Molecular Therapeutics, Graduate School of Medical Sciences, Kumamoto University, 1-1-1, Honjo, Chuo-ku, Kumamoto-Shi, Kumamoto-ken, 8608556, Japan.
  • Hayashi K; Department of Pharmacology and Molecular Therapeutics, Graduate School of Medical Sciences, Kumamoto University, 1-1-1, Honjo, Chuo-ku, Kumamoto-Shi, Kumamoto-ken, 8608556, Japan.
  • Takemoto Y; Department of Pharmacology and Molecular Therapeutics, Graduate School of Medical Sciences, Kumamoto University, 1-1-1, Honjo, Chuo-ku, Kumamoto-Shi, Kumamoto-ken, 8608556, Japan.
  • Cheng C; Department of Pharmacology and Molecular Therapeutics, Graduate School of Medical Sciences, Kumamoto University, 1-1-1, Honjo, Chuo-ku, Kumamoto-Shi, Kumamoto-ken, 8608556, Japan.
  • Takane K; Department of Pharmacology and Molecular Therapeutics, Graduate School of Medical Sciences, Kumamoto University, 1-1-1, Honjo, Chuo-ku, Kumamoto-Shi, Kumamoto-ken, 8608556, Japan.
  • Lin B; Department of Pharmacology and Molecular Therapeutics, Graduate School of Medical Sciences, Kumamoto University, 1-1-1, Honjo, Chuo-ku, Kumamoto-Shi, Kumamoto-ken, 8608556, Japan.
  • Komohara Y; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Kim-Mitsuyama S; Department of Pharmacology and Molecular Therapeutics, Graduate School of Medical Sciences, Kumamoto University, 1-1-1, Honjo, Chuo-ku, Kumamoto-Shi, Kumamoto-ken, 8608556, Japan. mitsuyam@kumamoto-u.ac.jp.
Cardiovasc Diabetol ; 16(1): 154, 2017 12 01.
Article in En | MEDLINE | ID: mdl-29195509

Full text: 1 Database: MEDLINE Main subject: Brain / Aging / Dipeptidyl Peptidase 4 / Aging, Premature / Dipeptidyl-Peptidase IV Inhibitors / Linagliptin / Glucuronidase Language: En Year: 2017 Type: Article

Full text: 1 Database: MEDLINE Main subject: Brain / Aging / Dipeptidyl Peptidase 4 / Aging, Premature / Dipeptidyl-Peptidase IV Inhibitors / Linagliptin / Glucuronidase Language: En Year: 2017 Type: Article