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EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer.
Oldrini, Barbara; Hsieh, Wan-Ying; Erdjument-Bromage, Hediye; Codega, Paolo; Carro, Maria Stella; Curiel-García, Alvaro; Campos, Carl; Pourmaleki, Maryam; Grommes, Christian; Vivanco, Igor; Rohle, Daniel; Bielski, Craig M; Taylor, Barry S; Hollmann, Travis J; Rosenblum, Marc; Tempst, Paul; Blenis, John; Squatrito, Massimo; Mellinghoff, Ingo K.
Affiliation
  • Oldrini B; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Hsieh WY; Seve Ballesteros Foundation Brain Tumor Group, Spanish National Cancer Research Centre, 28029, Madrid, Spain.
  • Erdjument-Bromage H; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Codega P; Department of Pharmacology, Weill Cornell Graduate School of Medical Sciences, New York, NY, 10065, USA.
  • Carro MS; Molecular Biology Program, Sloan Kettering Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Curiel-García A; Department of Biochemistry and Molecular Biology, Skirball Institute of Biomolecular Biology, New York University School of Medicine, New York, NY, 10016, USA.
  • Campos C; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Pourmaleki M; Department of Neurosurgery, University of Freiburg, 79106, Freiburg, Germany.
  • Grommes C; Seve Ballesteros Foundation Brain Tumor Group, Spanish National Cancer Research Centre, 28029, Madrid, Spain.
  • Vivanco I; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Rohle D; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Bielski CM; Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Taylor BS; Division of Cancer Therapeutics, The Institute of Cancer Research, London, SM2 5NG, UK.
  • Hollmann TJ; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Rosenblum M; Roche Oncology Discovery DTA Molecular Targeted Therapy Group, Basel, 4070, Switzerland.
  • Tempst P; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Blenis J; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Squatrito M; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Mellinghoff IK; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
Nat Commun ; 8(1): 2035, 2017 12 11.
Article in En | MEDLINE | ID: mdl-29229958
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Full text: 1 Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / Ran GTP-Binding Protein / Beta Karyopherins / ErbB Receptors / Glioma Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Year: 2017 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / Ran GTP-Binding Protein / Beta Karyopherins / ErbB Receptors / Glioma Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Year: 2017 Type: Article