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Quantifying the fitness cost of HIV-1 drug resistance mutations through phylodynamics.
Kühnert, Denise; Kouyos, Roger; Shirreff, George; Pecerska, Julija; Scherrer, Alexandra U; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Aubert, Vincent; Günthard, Huldrych F; Stadler, Tanja; Bonhoeffer, Sebastian.
Affiliation
  • Kühnert D; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
  • Kouyos R; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.
  • Shirreff G; Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland.
  • Pecerska J; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
  • Scherrer AU; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland.
  • Böni J; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
  • Yerly S; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.
  • Klimkait T; Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland.
  • Aubert V; School of Medicine, Imperial College London, London, United Kingdom.
  • Günthard HF; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
  • Stadler T; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland.
  • Bonhoeffer S; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
PLoS Pathog ; 14(2): e1006895, 2018 02.
Article in En | MEDLINE | ID: mdl-29462208
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Full text: 1 Database: MEDLINE Main subject: HIV Infections / HIV-1 / Anti-HIV Agents / Drug Resistance, Viral / Genetic Fitness / Mutation Rate Type of study: Clinical_trials / Health_economic_evaluation / Observational_studies Limits: Humans Country/Region as subject: Europa Language: En Year: 2018 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: HIV Infections / HIV-1 / Anti-HIV Agents / Drug Resistance, Viral / Genetic Fitness / Mutation Rate Type of study: Clinical_trials / Health_economic_evaluation / Observational_studies Limits: Humans Country/Region as subject: Europa Language: En Year: 2018 Type: Article