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Quantitative approach for cardiac risk assessment and interpretation in tuberculosis drug development.
Polak, Sebastian; Romero, Klaus; Berg, Alexander; Patel, Nikunjkumar; Jamei, Masoud; Hermann, David; Hanna, Debra.
Affiliation
  • Polak S; Certara-Simcyp, Level 2-Acero, 1 Concourse Way, Sheffield, S1 2BJ, UK.
  • Romero K; Unit of Pharmacoepidemiology and Pharmacoeconomics, Department of Social Pharmacy, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, Kraków, 30-217, Poland.
  • Berg A; Critical Path Institute, 1730 E. River Road, Tucson, AZ, 85705, USA. KRomero@c-path.org.
  • Patel N; Critical Path Institute, 1730 E. River Road, Tucson, AZ, 85705, USA.
  • Jamei M; Certara-Simcyp, Level 2-Acero, 1 Concourse Way, Sheffield, S1 2BJ, UK.
  • Hermann D; Certara-Simcyp, Level 2-Acero, 1 Concourse Way, Sheffield, S1 2BJ, UK.
  • Hanna D; Certara USA, Inc, Princeton, NJ, USA.
J Pharmacokinet Pharmacodyn ; 45(3): 457-467, 2018 06.
Article in En | MEDLINE | ID: mdl-29520534
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Full text: 1 Database: MEDLINE Main subject: Tuberculosis / Torsades de Pointes / Cardiotoxicity / Heart / Antitubercular Agents Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male Language: En Year: 2018 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Tuberculosis / Torsades de Pointes / Cardiotoxicity / Heart / Antitubercular Agents Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male Language: En Year: 2018 Type: Article