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The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin.
Galvan, Laurie; Francelle, Laetitia; Gaillard, Marie-Claude; de Longprez, Lucie; Carrillo-de Sauvage, Maria-Angeles; Liot, Géraldine; Cambon, Karine; Stimmer, Lev; Luccantoni, Sophie; Flament, Julien; Valette, Julien; de Chaldée, Michel; Auregan, Gwenaelle; Guillermier, Martine; Joséphine, Charlène; Petit, Fanny; Jan, Caroline; Jarrige, Margot; Dufour, Noëlle; Bonvento, Gilles; Humbert, Sandrine; Saudou, Frédéric; Hantraye, Philippe; Merienne, Karine; Bemelmans, Alexis-Pierre; Perrier, Anselme L; Déglon, Nicole; Brouillet, Emmanuel.
Affiliation
  • Galvan L; CEA, DRF, Institut François Jacob, Molecular Imaging Research Center (MIRCen), F-92265 Fontenay-aux-Roses, France.
  • Francelle L; CNRS, CEA, Paris-Sud Univ., Univ. Paris-Saclay, Neurodegenerative Diseases Laboratory (UMR9199), F-92265, Fontenay-aux-Roses, France.
  • Gaillard MC; CEA, DRF, Institut François Jacob, Molecular Imaging Research Center (MIRCen), F-92265 Fontenay-aux-Roses, France.
  • de Longprez L; CNRS, CEA, Paris-Sud Univ., Univ. Paris-Saclay, Neurodegenerative Diseases Laboratory (UMR9199), F-92265, Fontenay-aux-Roses, France.
  • Carrillo-de Sauvage MA; CEA, DRF, Institut François Jacob, Molecular Imaging Research Center (MIRCen), F-92265 Fontenay-aux-Roses, France.
  • Liot G; CNRS, CEA, Paris-Sud Univ., Univ. Paris-Saclay, Neurodegenerative Diseases Laboratory (UMR9199), F-92265, Fontenay-aux-Roses, France.
  • Cambon K; CEA, DRF, Institut François Jacob, Molecular Imaging Research Center (MIRCen), F-92265 Fontenay-aux-Roses, France.
  • Stimmer L; CNRS, CEA, Paris-Sud Univ., Univ. Paris-Saclay, Neurodegenerative Diseases Laboratory (UMR9199), F-92265, Fontenay-aux-Roses, France.
  • Luccantoni S; CEA, DRF, Institut François Jacob, Molecular Imaging Research Center (MIRCen), F-92265 Fontenay-aux-Roses, France.
  • Flament J; CNRS, CEA, Paris-Sud Univ., Univ. Paris-Saclay, Neurodegenerative Diseases Laboratory (UMR9199), F-92265, Fontenay-aux-Roses, France.
  • Valette J; CEA, DRF, Institut François Jacob, Molecular Imaging Research Center (MIRCen), F-92265 Fontenay-aux-Roses, France.
  • de Chaldée M; CNRS, CEA, Paris-Sud Univ., Univ. Paris-Saclay, Neurodegenerative Diseases Laboratory (UMR9199), F-92265, Fontenay-aux-Roses, France.
  • Auregan G; Univ. Grenoble Alpes, Grenoble Institut des Neurosciences, GIN, F38000, Grenoble, France.
  • Guillermier M; INSERM U1216, F38000, Grenoble, France.
  • Joséphine C; CHU de Grenoble, F38000, Grenoble, France.
  • Petit F; CEA, DRF, Institut François Jacob, Molecular Imaging Research Center (MIRCen), F-92265 Fontenay-aux-Roses, France.
  • Jan C; CNRS, CEA, Paris-Sud Univ., Univ. Paris-Saclay, Neurodegenerative Diseases Laboratory (UMR9199), F-92265, Fontenay-aux-Roses, France.
  • Jarrige M; CEA, DRF, Institut François Jacob, Molecular Imaging Research Center (MIRCen), F-92265 Fontenay-aux-Roses, France.
  • Dufour N; Inserm UMS27, F-92265 Fontenay-aux-Roses, France.
  • Bonvento G; CEA, DRF, Institut François Jacob, Molecular Imaging Research Center (MIRCen), F-92265 Fontenay-aux-Roses, France.
  • Humbert S; Inserm UMS27, F-92265 Fontenay-aux-Roses, France.
  • Saudou F; CEA, DRF, Institut François Jacob, Molecular Imaging Research Center (MIRCen), F-92265 Fontenay-aux-Roses, France.
  • Hantraye P; Inserm UMS27, F-92265 Fontenay-aux-Roses, France.
  • Merienne K; CEA, DRF, Institut François Jacob, Molecular Imaging Research Center (MIRCen), F-92265 Fontenay-aux-Roses, France.
  • Bemelmans AP; CNRS, CEA, Paris-Sud Univ., Univ. Paris-Saclay, Neurodegenerative Diseases Laboratory (UMR9199), F-92265, Fontenay-aux-Roses, France.
  • Perrier AL; Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Univ. Paris-Saclay, 91191 Gif-sur-Yvette Cedex, France.
  • Déglon N; CEA, DRF, Institut François Jacob, Molecular Imaging Research Center (MIRCen), F-92265 Fontenay-aux-Roses, France.
  • Brouillet E; CNRS, CEA, Paris-Sud Univ., Univ. Paris-Saclay, Neurodegenerative Diseases Laboratory (UMR9199), F-92265, Fontenay-aux-Roses, France.
Brain ; 141(5): 1434-1454, 2018 05 01.
Article in En | MEDLINE | ID: mdl-29534157
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Full text: 1 Database: MEDLINE Main subject: Protein Serine-Threonine Kinases / Huntington Disease / Corpus Striatum / Huntingtin Protein / Mutation Type of study: Prognostic_studies Limits: Animals Language: En Year: 2018 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Protein Serine-Threonine Kinases / Huntington Disease / Corpus Striatum / Huntingtin Protein / Mutation Type of study: Prognostic_studies Limits: Animals Language: En Year: 2018 Type: Article