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Novel N-substituted 5-aminosalicylamides as dual inhibitors of cyclooxygenase and 5-lipoxygenase enzymes: Synthesis, biological evaluation and docking study.
El-Nagar, Mohamed K S; Abdu-Allah, Hajjaj H M; Salem, Ola I A; Kafafy, Abdel-Hamid N; Farghaly, Hanan S M.
Affiliation
  • El-Nagar MKS; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.
  • Abdu-Allah HHM; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.
  • Salem OIA; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt. Electronic address: ola.salim@pharm.au.edu.eg.
  • Kafafy AN; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.
  • Farghaly HSM; Pharmacology Department, Faculty of Medicine, Assiut University, Assiut 71111, Egypt.
Bioorg Chem ; 78: 80-93, 2018 08.
Article in En | MEDLINE | ID: mdl-29550533
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Full text: 1 Database: MEDLINE Main subject: Stomach Ulcer / Salicylamides / Lipoxygenase Inhibitors / Cyclooxygenase Inhibitors / Molecular Docking Simulation / Anti-Ulcer Agents Limits: Animals Language: En Year: 2018 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Stomach Ulcer / Salicylamides / Lipoxygenase Inhibitors / Cyclooxygenase Inhibitors / Molecular Docking Simulation / Anti-Ulcer Agents Limits: Animals Language: En Year: 2018 Type: Article