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LSD1 activates a lethal prostate cancer gene network independently of its demethylase function.
Sehrawat, Archana; Gao, Lina; Wang, Yuliang; Bankhead, Armand; McWeeney, Shannon K; King, Carly J; Schwartzman, Jacob; Urrutia, Joshua; Bisson, William H; Coleman, Daniel J; Joshi, Sunil K; Kim, Dae-Hwan; Sampson, David A; Weinmann, Sheila; Kallakury, Bhaskar V S; Berry, Deborah L; Haque, Reina; Van Den Eeden, Stephen K; Sharma, Sunil; Bearss, Jared; Beer, Tomasz M; Thomas, George V; Heiser, Laura M; Alumkal, Joshi J.
Affiliation
  • Sehrawat A; Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239.
  • Gao L; Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239.
  • Wang Y; Biomedical Engineering, Oregon Health & Science University, Portland, OR 97239.
  • Bankhead A; Computational Biology, Oregon Health & Science University, Portland, OR 97239.
  • McWeeney SK; Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109.
  • King CJ; Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239.
  • Schwartzman J; Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR 97239.
  • Urrutia J; Biomedical Engineering, Oregon Health & Science University, Portland, OR 97239.
  • Bisson WH; Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239.
  • Coleman DJ; Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239.
  • Joshi SK; Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR 97331.
  • Kim DH; Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239.
  • Sampson DA; Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239.
  • Weinmann S; Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239.
  • Kallakury BVS; Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239.
  • Berry DL; Center for Health Research, Kaiser Permanente NW, Portland, OR 97227.
  • Haque R; Pathology, Medstar Georgetown University Hospital, Washington, DC 20007.
  • Van Den Eeden SK; Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057.
  • Sharma S; Research and Evaluation, Kaiser Permanente, Pasadena, CA 91101.
  • Bearss J; Division of Research, Kaiser Permanente Northern California, Oakland, CA 94612.
  • Beer TM; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112.
  • Thomas GV; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112.
  • Heiser LM; Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239.
  • Alumkal JJ; Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239.
Proc Natl Acad Sci U S A ; 115(18): E4179-E4188, 2018 05 01.
Article in En | MEDLINE | ID: mdl-29581250
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Full text: 1 Database: MEDLINE Main subject: Gene Regulatory Networks / Histone Demethylases / Prostatic Neoplasms, Castration-Resistant / Neoplasm Proteins Limits: Humans / Male Language: En Year: 2018 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Gene Regulatory Networks / Histone Demethylases / Prostatic Neoplasms, Castration-Resistant / Neoplasm Proteins Limits: Humans / Male Language: En Year: 2018 Type: Article