Influence of Polysorbate 60 on Formulation Properties and Bioavailability of Morin-Loaded Nanoemulsions with and without Low-Saponification-Degree Polyvinyl Alcohol.

Ikeuchi-Takahashi, Yuri; Kobayashi, Ayaka; Ishihara, Chizuko; Matsubara, Takumi; Matsubara, Hiroaki; Onishi, Hiraku

Ikeuchi-Takahashi, Yuri; Kobayashi, Ayaka; Ishihara, Chizuko; Matsubara, Takumi; Matsubara, Hiroaki; Onishi, Hiraku.

Affiliation

Ikeuchi-Takahashi Y; Department of Drug Delivery Research, Hoshi University.
Kobayashi A; The Nippon Synthetic Chemical Industry Co., Ltd.
Ishihara C; The Nippon Synthetic Chemical Industry Co., Ltd.
Matsubara T; Department of Drug Delivery Research, Hoshi University.
Matsubara H; Department of Drug Delivery Research, Hoshi University.
Onishi H; Department of Drug Delivery Research, Hoshi University.

Biol Pharm Bull ; 41(5): 754-760, 2018.

Article in En | MEDLINE | ID: mdl-29709912

Subject(s)

Flavonoids; Nanoparticles; Polysorbates; Polyvinyl Alcohol; Administration, Oral; Animals; Biological Availability; Drug Compounding; Drug Liberation; Emulsions; Flavonoids/administration & dosage; Flavonoids/blood; Flavonoids/chemistry; Flavonoids/pharmacokinetics; Male; Mice, Inbred ICR; Nanoparticles/administration & dosage; Nanoparticles/chemistry; Polysorbates/administration & dosage; Polysorbates/chemistry; Polysorbates/pharmacokinetics; Polyvinyl Alcohol/administration & dosage; Polyvinyl Alcohol/chemistry; Polyvinyl Alcohol/pharmacokinetics

Key words

P-glycoprotein; bioavailability; morin; nanoemulsion; polyvinyl alcohol

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Full text: 1 Database: MEDLINE Main subject: Polysorbates / Polyvinyl Alcohol / Flavonoids / Nanoparticles Limits: Animals Language: En Year: 2018 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Polysorbates / Polyvinyl Alcohol / Flavonoids / Nanoparticles Limits: Animals Language: En Year: 2018 Type: Article