Hypoxia and tumor angiogenesis in the era of hepatocellular carcinoma transarterial loco-regional treatments.
Future Oncol
; 14(28): 2957-2967, 2018 Dec.
Article
in En
| MEDLINE
| ID: mdl-29712486
ABSTRACT
This review focuses upon interactions and potential therapeutic targets in the 'vicious cycle' between hypoxia and neoangiogenesis following treatment of hepatocellular carcinoma with transarterial loco-regional therapies. Biomarkers correlated with angiogenesis have been studied by many authors as prognostic determinants following transarterial intrahepatic therapy. According to these results future therapies directed toward specific factors related to angiogenesis could play a significant role in preventing local tumor recurrence and remote metastasis.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Carcinoma, Hepatocellular
/
Liver Neoplasms
/
Hypoxia
/
Neovascularization, Pathologic
Type of study:
Prognostic_studies
Limits:
Humans
Language:
En
Year:
2018
Type:
Article